Pre-analysis commitments compatible with adaptive experimentation
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C12 — Hypothesis Testing: General Economics catalogue openaigpt 6 astra ultra 35% cataloguednot recordedOpenStatement
CI-07 | Econometric theory and causal inference
Research agenda formalization
Definitions and assumptions
Fix a filtration $(\mathcal F_t)$ recording observed data and authorized external randomness. A pre-analysis commitment is a prespecified measurable program $\mathcal A$ mapping each history to the next assignment kernel, target definition, eligibility rule, testing rule, and permitted future updates. Thus the program is fixed before data collection although its realized outputs are adaptive. Every new target or hypothesis must record the sigma-field on which its selection depends and the observations subsequently used for inference.In a concrete class, outcomes are bounded, allocation is conditionally randomized with known positive probabilities, and new hypotheses use future observations or a declared selection correction. The program obeys a specified expected treatment-budget constraint. Let $V_t(\mathcal A)$ count false rejections and let $U_T(\mathcal A,P)$ count rejections of prespecified effect alternatives by horizon $T$; discovery utility is $\E_P[U_T(\mathcal A,P)]$.
Formal question
Characterize operational, checkable conditions on permitted history-dependent updates that guarantee \[ \sup_{P\in\mathcal M}\Pr_P\{\exists t:V_t(\mathcal A)>0\} \leq\alpha. \] Among programs satisfying that guarantee and the budget, determine optimal achievable discovery utility over a declared alternative class, or minimax regret relative to an oracle program given the same budget. Require nontrivial power for effects exceeding specified separations. Characterize when conditional supermartingale tests continue to be valid after changes in allocation, outcomes, eligibility, or the target.Scope and status
The formal commitment is a rule for adaptation, rather than an irrevocable list of realized design choices. Its mathematical validity depends on the information used by each update. Broad automation or pre-analysis-plan guidance does not itself establish error control, and unconstrained post-selection changes cannot be declared valid by registration alone. Basic predictable testing constructions exist; the attached challenge motivates the design-and-power refinement.References for the source of the problem
Carlos Cinelli, Avi Feller, Guido Imbens, Edward Kennedy, Sara Magliacane, and Jose Zubizarreta, Challenges in Statistics: A Dozen Challenges in Causality and Causal Inference, arXiv:2508.17099v1, 23 August 2025, Section 3.1.3, paragraph Automation and reducing frictions. https://arxiv.org/html/2508.17099v1.Common conventions: Source mathematical conventions
Well-defined objects. All probability spaces and measurable variables are specified or inherited from a local statistical model. Expectations used as finite targets require the stated integrability. A decision rule or estimator is measurable with respect to its available information; randomized rules may use an auxiliary independent random variable. Norms without a subscript are Euclidean in finite-dimensional spaces. An optimizer is requested only when attainment is assured; otherwise the question concerns the optimal value and $\varepsilon$-optimal admissible rules for every $\varepsilon>0$.
Identification. A structural model $m\in\mathcal M$ implies an observable law $P_m^{\rm obs}$ and target $\theta(m)$. The target is point identified on $\mathcal M$ if \[ P_{m_1}^{\rm obs}=P_{m_2}^{\rm obs} \quad\Longrightarrow\quad\theta(m_1)=\theta(m_2) \qquad(m_1,m_2\in\mathcal M). \] When this fails, the sharp identified set is \[ \Theta(P;\mathcal M)=\{\theta(m):m\in\mathcal M, P_m^{\rm obs}=P\}. \] Specifying an intervention or estimand does not establish identification. Positivity, exclusion, causal sufficiency, measurement restrictions, and transport assumptions are substantive local inputs, never automatic consequences of notation.
Minimax risk and nontrivial inference. For a statistical experiment with data law $P^{(n)}$, target $\theta(P)$, and nonnegative loss $\ell$, define \[ \mathcal R_n(\mathcal P,\ell) =\inf_{\widehat\theta_n}\sup_{P\in\mathcal P} \E_{P^{(n)}}\ell(\widehat\theta_n,\theta(P)). \] The infimum is over measurable estimators. A sharp rate is a sequence $r_n$ for which $0<c\leq C<\infty$, independent of $n$, satisfies $c r_n\leq\mathcal R_n\leq C r_n$ for all sufficiently large $n$. Squared-error parametric risk is of order $n^{-1}$; the corresponding root-mean-squared error is of order $n^{-1/2}$. These different conventions are distinguished locally. A uniform asymptotic confidence region $C_n$ must satisfy \[ \liminf_{n\to\infty}\inf_{P\in\mathcal P} \Pr_{P^{(n)}}\{\theta(P)\in C_n\}\geq 1-\alpha, \qquad 0<\alpha<1, \] together with an informative diameter or expected-width requirement. Coverage alone permits the vacuous whole parameter space. Testing questions similarly impose both size control and power against a declared separated alternative class.
Binary causal baseline. When an entry explicitly invokes this baseline, one observes independent copies of $O=(X,W,Y)$, with $W\in\{0,1\}$ and potential outcomes $Y(0),Y(1)$. Assume consistency $Y=Y(W)$, no interference, conditional exchangeability $(Y(0),Y(1))\perp W\mid X$, and overlap $\epsilon\leq e(X)\leq1-\epsilon$ almost surely for a fixed $0<\epsilon<1/2$, where \[ e(x)=\Pr(W=1\mid X=x),\qquad m_w(x)=\E[Y\mid W=w,X=x],\qquad \tau(x)=m_1(x)-m_0(x). \] These assumptions identify conditional mean effects almost everywhere under the covariate law. Pointwise or uniform effects require appropriate regularity and a specified support. Continuous treatment, longitudinal data, adaptive experiments, and network interference require their own assumptions in place of this baseline. Bounded outcomes, densities, and smoothness are additional assumptions only where stated.
Function classes. On $[0,1]^d$, $\mathcal H_d^s(L)$ is the isotropic Hölder ball of radius $L>0$: put $k=\lceil s\rceil-1$ and $\gamma=s-k\in(0,1]$, bound derivatives through order $k$, and require the order-$k$ derivatives to be $\gamma$-Hölder with constant at most $L$. Thus integer orders use a Lipschitz final derivative convention. The class $\operatorname{BV}_d(L)$ consists of functions $f\in L^1((0,1)^d)$ whose distributional derivative is a finite vector measure and for which $\|f\|_{L^1}+|Df|((0,1)^d)\leq L$. An $L^\infty$ bound or a particular pointwise version is imposed separately when needed. Sparse and neural-network classes require a declared dictionary or architecture and coefficient bounds.
An anisotropic Hölder class with declared block smoothness indices means coordinatewise Hölder regularity in each block, uniformly in the other blocks, with all corresponding derivative and Hölder bounds at most the stated radius. Derivative orders and the integer-order convention in each block are those just given. Mixed-derivative bounds are additional restrictions only when explicitly stated.
Decision and computational questions. Policy regret compares admissible feasible policies under the same law and constraints. In computational entries, finite data and thresholds have rational encodings; running time is measured in their total bit length. Real-valued equilibrium search uses the explicitly declared algebraic or FIXP encoding. An approximation ratio for maximization is written $\operatorname{OPT}/\operatorname{ALG}$ and for minimization as $\operatorname{ALG}/\operatorname{OPT}$, with zero optima and infeasible instances handled locally. Historical approximation bounds are not automatically current bounds.
Statement licence: CC-BY-4.0 · Source file
Contributions 1
GPT 6 Astra Ultra attempt on Econ-129
Problem ID: C12-126 Model: GPT 6 Astra Ultra Version: 1
Pre-analysis commitments compatible with adaptive experimentation
Status. Unresolved for optimal discovery across general adaptive targets. The results below give a checkable commitment rule and a treatment-budget separation bound in one restricted experiment.
Short problem and statistical model
A pre-analysis commitment fixes a measurable program before observations arrive. The program may adapt allocations and create hypotheses; the aim is familywise error at most $\alpha$ at every time and useful discovery power under an expected treatment budget. Let $\mathcal F_t$ contain observations and authorized randomness through time $t$. A launched test $j$ has stopping-time launch $\sigma_j$, an $\mathcal F_{\sigma_j}$-measurable level $a_j\geq0$, and subsequently observed scores $X_{jt}\in[-1,1]$. Its null is the conditional assertion \[ H_j:\quad {\mathbb{E}}[X_{jt}\mid\mathcal F_{t-1}]\leq0\quad(t>\sigma_j). \] A newly chosen target must meet this assertion under its claimed null after conditioning on the history that chose it. Unconditional zero means are insufficient. Assume countably many launches and $\sum_j a_j\leq\alpha$ almost surely. A test with $a_j=0$ never rejects. For each fixed sampling law, whether a launched hypothesis is true is required to be measurable at its launch; its conditional score restriction must hold on all such true-null launch histories.For example, at time $t$ let potential outcomes lie in $[0,1]$, randomize $W_t$ with predictable known $p_t\in[\epsilon,1-\epsilon]$, independently of that unit's potential outcomes conditional on past information. Set \[ X_t=\epsilon\left\{\frac{W_tY_t}{p_t} -\frac{(1-W_t)Y_t}{1-p_t}-\theta_0\right\}/2, \qquad \theta_0\in[-1,1]. \] Then $|X_t|\leq1$, and its conditional mean is nonpositive if the next unit's conditional treatment effect is at most $\theta_0$. Changing eligibility or outcomes is valid only if the updated score still has this property. A null about a population average alone need not imply it for outcome-adaptively selected subpopulations.