## Problem 166 — rank:279

**Title:** Total effect of linked selection

**Added binding assumptions (LaTeX):**

```latex
The decomposition is an algebraic identity after the four positive-denominator counterfactuals are defined; the unresolved part is their biological identification and accurate calculation. The interaction term can have either sign and is not a uniquely attributable mechanism share. Specify whether fitness effects and mutation supply remain fixed when turning each selection component off, and report a joint confidence region rather than separately overconfident marginal estimates.
```

**Direct edits:** 0. **Fresh external checks:** None; supplied sources retained as provenance.