## Problem 226 — rank:252

**Title:** Nuclear-receptor and AhR immune crosstalk

**Added binding assumptions (LaTeX):**

```latex
The identifiable object is the set of graph topologies induced by all parameters with the same observed law; there is no separate optimization over a ``smallest'' equivalence class without an additional criterion. Distinguish a nonzero coefficient in a chosen basis from a nonzero derivative over the stated domain. A sign-supported edge needs a nonzero margin; derivatives that can vanish or change sign remain context-dependent or unresolved.
```

**Direct edits:** 1. **Fresh external checks:** None; supplied sources retained as provenance.