## Problem 134 — rank:87

**Title:** Mechanical feedback on gene expression

**Added binding assumptions (LaTeX):**

```latex
State whether $g$ is per-cell normalized expression or a concentration density; only the latter necessarily requires a dilution term in material transport. Mechanical stress must enter regulatory response through an explicitly frame-consistent tensor map or objective features. Close the mechanics and declare feasible mechanical interventions. Correlation between stress and gene expression does not identify either direction of the proposed feedback.
```

**Direct edits:** 0. **Fresh external checks:** None; supplied sources retained as provenance.