## Problem 046 — rank:59

**Title:** Gene-regulatory-network reconstruction

**Added binding assumptions (LaTeX):**

```latex
Use differentiable drift functions on a stated reachable open domain to define the edge set. Specify $\eta$ as a random integrable input, or replace the equation by an SDE with an explicit diffusion law. Prediction loss compares conditional means or complete laws; squared distance between independent noisy realizations contains irreducible variance. A predictive graph need not identify all direct biochemical edges.
```

**Direct edits:** 0. **Fresh external checks:** SC03