## Problem 247 — rank:37

**Title:** Drivers of paediatric solid tumours

**Added binding assumptions (LaTeX):**

```latex
For a causal driver-set interpretation, require the reference configuration to have neoplastic risk below the sufficiency threshold by a fixed margin; otherwise the empty set can be sufficient without identifying a contribution. Minimality is inclusion-minimality, not minimum cardinality. The joint intervention must preserve the declared developmental context and remaining reference alterations. Distinguish conceptual causal claims from observed enrichment or selection among diagnosed tumors.
```

**Direct edits:** 0. **Fresh external checks:** None; supplied sources retained as provenance.