## Problem 076 — rank:64

**Title:** Cell–cell communication from spatial omics

**Added binding assumptions (LaTeX):**

```latex
Define the intervention on available ligand protein or secretion, not interchangeably on transcript abundance. Potential outcomes depend on the full sender-intervention vector because other senders and receptor competition create interference; hold those components fixed or average over a declared policy. Give simultaneous interval coverage or FDR control when thresholding many edges.
```

**Direct edits:** 0. **Fresh external checks:** None; supplied sources retained as provenance.